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Synonyms
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Why do we do this test?
Measures both albumin and globulins except proteins in the clotting cascade.
1. Coupled TP with albumin give s clue in
hyperglobulinemia ( MGUS, Multiple
myeloma, lymphoma)
2. Low values are seen in primary and
secondary humoral immunodeficiency.
3. Spot urine protein / creatinine ratio and 24
hour urinary protein excretion is done to
assess the urinary protein excretion
4. In CSF protein is done to differete the
pyogenic causes from viral causes of
meningitis
5. In body fluids especially in plural fluid
protein is done couples with serum protein
to differentiate educate from transudate.
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Specimen Type
Serum, Plasma (EDTA), Plasma (Li Heparin), Urine (spot/ timed collection), CSF, Body Fluid
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Instructions for specimen
collection & Patient preparation
No special preparation is needed
Better blood is drawn without touniquet or touniquet less than 1 minute
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Specimen transportation &
Processing
Transport in room temperature
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Specimen storage & stability
1. At 4°C up to 3 days
2. At -20°C up to 6 months
3. At -70°C long term storage
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Specimen storage duration
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Reference Intervals & Target
Values
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Critical Limits
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Possible Pre-analytical Errors
1. Spuriously high values if there is
prolonged stasis during phelebotomy
2. Values of urinary excretion would be
spuriously low or high if not properly
collected
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Possible Analytical Errors
Haemolysis 10 g/L might cause positive interference
Icterus causes negative interference
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Available Government Laboratories
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Recommended turnaround time
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Test Method
Blood - Biuret method, Body fluids - dye binding method (Eg. Pyrogallol red)
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Documentation
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References
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Last Updated : 2020-09-23 04:19:45 |
