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Prostate Specific Antigen - Total
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Synonyms
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Why do we do this test?
PSA is measured to screen for carcinoma prostate, to assist in the diagnosis, to assess the response to therapy and in the long term follow up to detect recurrences.
PSA is a protein produced by both cancerous and non- cancerous tissues in the prostate.
High levels of PSA are found in prostatic cancer. But marginally high levels are found in benign prostatic hyperplasia (BPH) and in elderly. Interpretation of your PSA value therefore should be done with consultation with your doctor.
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Specimen Type
| Serum, Plasma (EDTA), Plasma (Li Heparin) |
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Instructions for specimen
collection & Patient preparation
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Specimen transportation &
Processing
Transport separated serum/plasma in ice (2-8C). If prolonged storage store
at -20 C.
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Specimen storage & stability
Separate serum as soon as possible.
For prolonged storage keep frozen at -20C. If analysis within 5 days stable at 0C.
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Specimen storage duration
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Reference Intervals & Target
Values
Age
<40 yrs <1.3 ng/mL
41 - 50 yrs <2.0 ng/mL
51 – 60 yrs <3.3 ng/mL
61 – 70 yrs <4.0 ng/mL
>70 yrs <4.5 ng/mL
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Critical Limits
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Possible Pre-analytical Errors
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Possible Analytical Errors
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Insufficient serum/plasma volume, Air bubbles, Fibrin clots.
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Available Government Laboratories
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Apeksha Hospital, National Hospital Sri Lanka, Medical Research Institute, National Hospital Kandy, Teaching Hospital Jaffna, North Colombo Teaching Hospital, Karapitiya Teaching Hospital
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Recommended turnaround time
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Test Method
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Documentation
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References
1. Daniel W.Chan, Stewart Sell; Tumour Markers. Burtis CA, Ashwood ER. Tietz Text Book of Clinical Chemistry,3rd edition, USA, Elsevier Saunders 1999, 722-749
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Last Updated : 2020-09-14 05:07:37 |
